“Doctor Lab Panda” reveals the case of “Ae Pornthip”, the mutated EGFR gene is the cause of cancer. What is the trigger?
Lung cancer of “Ae Pornthip” and the EGFR gene mutation that is common in non-smoker Asian women
After famous actor Po Nattawut Sakidjai revealed the news. That his beloved wife Ae Pornthip had lung cancer, shocking fans and people in the entertainment industry, the Facebook page “Mor Lab Panda” by Dr. Pakpoom Dechhasadin has come out to explain more about the cause of a type of lung cancer that often occurs in Asian women. Especially those who do not smoke.
EGFR mutations: the trigger for cancer cells
In your case, Ae Pornthip, the doctor said it was caused by a mutation of EGFR (Epidermal Growth Factor Receptor). A สมัคร UFABET วันนี้ รับเครดิตฟรีสำหรับสมาชิกใหม่ protein found on the surface of human cells. EGFR acts like a “switch” controlling cell growth and repair.
But when the mutation occurs, this switch will stay in the “always on” position, causing:
- Cells divide non-stop: Cells multiply rapidly.
- Cells Never Die: Lack of Control Allows Cells to Survive Even When They Should Die
- Spreads easily: Has the ability to spread to other organs more quickly.
In particular, common mutations in EGFR include:
- Missing fragment in Exon 19
- Genetic changes in Exon 21
Both types cause EGFR signaling to go off track and cause a type of lung cancer (NSCLC) that is more common in non-smoker Asian women.
PM2.5 may be a trigger
Although there is no clear evidence to indicate what is the main cause of EGFR mutation, Dr. Lab Panda explains that PM2.5 or fine dust may be an important factor because it can cause DNA damage and cause cell mutation.
Environmental toxins, such as air pollution, toxic fumes, or carcinogens, are all risk factors that may lead to gene changes in lung cells.
Fortunately, it is detected early – stage 1 cancer is curable.
In misfortune, there is still good fortune because Ms. Ae Pornthip was diagnosed with the disease in the early stages or stage 1 , which is considered a stage with a high chance of being cured if she receives proper and timely treatment.
Dr. Lab Panda also sent encouragement to the Po-Ae family and asked everyone to observe their bodies and get regular check-ups, stating:
“Take care of your health, everyone. I would like to give my support to Phi Po, Khun Ae, and your family. Fight! I hope you get well soon!”